...is an expression of affirmation and is used the same way as "Okay", "Go On" or "Go Ahead" depending on the situation. It's Tagalog equivalent would be "Sige". Saying "douzo" is usually associated with a hand gesture of affirmation be it a thumbs up, extending an open palm, or a nod. An example situation would be if someone wants to pass and says "Excuse me". You make way for the person to pass by, extend your hand to the free way, and say "douzo". A thumbs up would be cheerful and nice, but rather exaggerated.